ABSTRACT
The objective of this study was to evaluate the effects of an hCG sub dose applied at the Hou Hai acupoint on corpus luteum (CL) quality and ovulation induction in mares. Fifteen crossbred mares were distributed in randomized blocks and used in three periods with each period employed as the blocking factor in three treatments: T1 = 1500 IU of hCG via intravenous (IV); T2 = 450 IU of hCG applied at the false acupoint (IV); and T3 = 450 IU of hCG applied at the Hou Hai acupoint. Mean diameter of the CL, serum concentration of progesterone (P4), vascularization of the pre-ovulatory follicle and CL were evaluated. Females administered 450 IU of hCG at the Hou Hai acupoint exhibited greater ovulation rates (33.33%) 48h after induction; The minimum number of colored pixel (NCP) of the pre-ovulatory follicle of control females was superior (40.33) to that of mares administered 450 IU of hCG IV at the false acupoint (36.84) and similar to that of those administered hCG at the Hou Hai acupoint (39.31). Further, moderately positive correlations were found between the CL diameter and the P4 concentration on D8 (P<0.05). IV administration of 450 IU of hCG or at the Hou Hai acupoint was efficient at inducing ovulation and ensuring the quality of CL in mares.(AU)
O objetivo foi avaliar os efeitos de uma subdose de hCG aplicada no acuponto Hou Hai na qualidade do corpo lúteo (CL) e na indução da ovulação em éguas. Quinze éguas mestiças foram distribuídas em blocos ao acaso, sendo o período utilizado como fator de blocagem, em: T1 = 1500 UI de hCG por via intravenosa (IV); T2 = 450 UI de hCG aplicado no falso acuponto (IV) e T3 = 450 UI de hCG aplicada no acuponto Hou Hai. Avaliou-se diâmetro médio do CL, concentração sérica de progesterona (P4), vascularização do folículo pré-ovulatório e do CL. As fêmeas que receberam 450 UI de hCG no acuponto Hou Hai apresentaram maiores taxas de ovulação (33,33%) 48h após a indução. O número de pixels coloridos (NPC) mínimo do folículo pré-ovulatório das fêmeas do grupo controle foi superior (40,33) ao das éguas que receberam 450 UI de hCG IV no falso acuponto (36,84) e semelhante ao das éguas que receberam hCG no acuponto Hou Hai (39,31); correlações moderadamente positivas foram encontradas entre o diâmetro do CL e a concentração de P4, ambos no D8 (P <0,05). A administração IV de 450 UI de hCG ou no acuponto Hou Hai foi eficiente na indução da ovulação e na garantia da qualidade do CL nas éguas.(AU)
Subject(s)
Animals , Female , Ovulation Induction/methods , Progesterone/administration & dosage , Acupuncture Points , Corpus Luteum/drug effects , Chorionic Gonadotropin/administration & dosage , Horses/physiology , Ovulation Induction/veterinary , Ultrasonography, Doppler/veterinaryABSTRACT
Introducción: El síndrome de disfunción temporomandibular constituye un problema de salud importante, que afecta a más de 50 % de la población mundial. Objetivo: Describir la evolución terapéutica de pacientes con afecciones temporomandibulares tratados con farmacopuntura. Métodos: Se realizó un estudio descriptivo de 60 pacientes con síndrome de disfunción temporomandibular en fase aguda, atendidos en el Hospital Clinicoquirúrgico Faustino Pérez de Matanzas, desde enero hasta diciembre de 2018. Se administró una solución compuesta por lidocaína, vitamina B12 y betametasona en puntos acupunturales determinados. Además, se utilizó la escala verbal del dolor. Resultados: Se encontró que el grupo etario de 60 años y más, así como el sexo femenino fueron los más afectados. De los factores asociados a este síndrome predominó el estrés en 100 % de los pacientes; 63,3 % presentaron dolor moderado y 53,3 % se aliviaron totalmente. Conclusiones: La farmacopuntura alivió el dolor asociado al síndrome de disfunción temporomandibular en la mayoría de los afectados, entre las 3 primeras sesiones de tratamiento.
Introduction: The temporomandibular dysfunction syndrome constitutes an important health problem that affects more than 50 % of the world population. Objective: To describe the therapeutic clinical course of patients with temporomandibular affections treated with pharmacopuncture. Methods: A descriptive study of 60 patients with temporomandibular dysfunction syndrome in acute phase was carried out, they were assisted in the Faustino Pérez Clinical Surgical Hospital from Matanzas, from January to December, 2018. A solution composed by lidocaine, B12 vitamin and betamethasone was administered in certain acupunctural points. Also, the pain verbal scale was used. Results: It was found that the 60 years and over age group, as well as the female sex were those most affected. Of the factors associated to this syndrome stress prevailed in 100 % of patients; 63.3 % presented moderate pain and 53.3 % were totally relieved. Conclusions: Pharmacopuncture relieved the pain associated with the temporomandibular dysfunction syndrome in most of those affected, in the first 3 treatment sessions.
Subject(s)
Temporomandibular Joint Dysfunction Syndrome , Temporomandibular Joint Dysfunction Syndrome/drug therapy , Acupuncture , Medicine, TraditionalABSTRACT
Se realizó un estudio de intervención terapéutica en 40 pacientes, quienes acudieron al departamento de la Clínica del Dolor de Santiago de Cuba por presentar bursitis del hombro, desde enero hasta diciembre del 2014, con vistas a evaluar la efectividad de la farmacopuntura en dichos pacientes. Entre las variables de interés figuraron: edad, sexo y síntomas más frecuentes. Se halló predominio del sexo masculino (65,0 %) y del dolor (100,0 %). Luego de las 3 primeras sesiones se observó una mejoría, pues 80,0 % de los síntomas desaparecieron. Los resultados obtenidos evidenciaron la efectividad de esta terapéutica en 95,0 % de los afectados.
A therapeutic intervention study in 40 patients who went to the Pain Clinic department in Santiago de Cuba due to shoulder bursal synovitis, was carried out from January to December, 2014, aimed at evaluating the effectiveness of pharmacopuncture in these patients. Among the variables of interest there were: age, sex and most frequent symptoms. There was a prevalence of the male sex (65.0%) and pain (100.0%). After the first 3 sessions an improvement was observed, because 80.0% of the symptoms disappeared. The obtained results evidenced the effectiveness of this therapy in 95.0% of those affected.
Subject(s)
Bursitis , Acupuncture , Pain , Secondary CareABSTRACT
INTRODUCCIÓN: estudios demuestran que más del 40 % de los pacientes sufren dolor en el posoperatorio inmediato, y tres de cada cuatro lo experimentan los dos primeros días. OBJETIVO: evaluar la efectividad de la farmacopuntura con tramadol en la prevención del dolor posoperatorio en pacientes operados de hernia inguinal. MÉTODOS: estudio prospectivo, descriptivo, aleatorio y controlado a 60 pacientes operados de manera electiva de herniorrafia inguinal en el Hospital Militar Central "Dr. Carlos J. Finlay" en el período de septiembre de 2010 a septiembre de 2011. Se conformaron dos grupos de igual cantidad de pacientes: grupo F (estudio) en el que se aplicó farmacopuntura con tramadol 12,5 mg en los puntos del meridiano de estómago (E36, E44) y anestesia regional subaracnoidea, y el grupo C (control) en el que se empleó tramadol 100 mg por vía intramuscular e igual método anestésico. Se evaluó el dolor posoperatorio, según criterios del paciente por ubicación en la escala análoga visual. RESULTADOS: predominó el sexo masculino y el rango de más de 60 años de edad. Los pacientes que recibieron el método de anestesia-analgesia y farmacopuntura presentaron mayor grado de analgesia posoperatoria con ausencia completa de dolor en 60 %, con menor cantidad de náuseas y vómitos posoperatorios y una excelente estabilidad hemodinámica. CONCLUSIONES: la farmacopuntura con tramadol constituye un método terapéutico analgésico en la prevención del dolor posoperatorio.
INTRODUCTION: studies have shown that over 40 % of patients suffer from pain in the immediate postoperative period, and three out of every four during the first two days. OBJECTIVE: evaluate the effectiveness of pharmacopuncture with tramadol to prevent postoperative pain in patients undergoing surgery for inguinal hernia. METHODS: a prospective descriptive randomized controlled study was conducted of 60 patients electively operated on for inguinal hernia at Dr. Carlos J. Finlay Central Military Hospital from September 2010 to September 2011. Patients were divided into two equal groups: Group F (study) received pharmacopuncture with tramadol 12.5 mg at stomach meridian acupoints (E36, E44) and regional subarachnoid anaesthesia, and Group C (control) received intramuscular tramadol 100 mg and the same anaesthetic procedure. Postoperative pain was ranked on the visual analog scale based on criteria provided by patients. RESULTS: there was a predominance of the male sex and the over-60 age group. Patients receiving anaesthesia-analgesia and pharmacopuncture showed greater postoperative analgesia, with total absence of pain in 60 %, less postoperative nausea and vomiting, and excellent hemodynamic stability. CONCLUSIONS: pharmacopuncture with tramadol constitutes an analgesic therapeutic method to prevent postoperative pain.
Subject(s)
Humans , Male , Middle Aged , Pain, Postoperative/therapy , Acupuncture Analgesia/statistics & numerical data , Infiltration-Percolation/adverse effects , Herniorrhaphy , Hernia, Inguinal/surgery , Anesthesia, Conduction/statistics & numerical data , Epidemiology, Descriptive , Prospective StudiesABSTRACT
Foi realizado um estudo para investigar a tranquilização de cães com subdose de acepromazina no acuponto yin tang, localizado no ponto médio de uma linha traçada entre os cantos laterais dos olhos. O estudo foi delineado em quatro protocolos, utilizando-se oito cães. No primeiro protocolo (P1) foi administrada acepromazina no yin tang em subdose (0,01mg/ kg). No segundo protocolo (P2) foi administrada a mesma dose utilizada em P1 por via intramuscular (IM). No terceiro protocolo (P3) foi administrada dose terapêutica (0,1mg/kg) IM. No quarto protocolo (P4) foi colocada uma agulha de acupuntura no yin tang. Durante as etapas foram aferidos: frequência cardíaca (FC), frequência respiratória (FR) e temperatura retal (TR). Tais aferições foram realizadas antes dos tratamentos, quinze minutos após a administração do fármaco e de quinze em quinze minutos até duas horas. Nos mesmos momentos foi pesquisada a presença ou ausência de decúbito, sonolência, ptose palpebral e outros sinais de tranquilização. Os dados foram analisados estatisticamente. No tratamento experimental (P1) dois cães apresentaram tranquilização satisfatória e um moderada, sem diferença significativa com o grupo no qual se administrou acepromazina em dose terapêutica IM. Concluiu-se que a administração de acepromazina em subdose no acuponto Yin Tang pode ser usada com segurança na rotina clínica nas mais diversas manipulações nas quais haja necessidade de tranquilização de cães...
A study was conducted to investigate the tranquilization of dogs using a subdose of acepromazine in the yin tang acupoint located in the medium point of a line drawn between the lateral corners of the eyes. The study was designed in four protocols using eight dogs. In the first protocol (P1), acepromazine was administered in yin tang in subdose (0.01mg/kg). In the second protocol (P2), the same dose as in P1 was administered by intramuscular route (IM). In the third protocol (P3), a therapeutic dose (0.1 mg/kg) was administered IM. In the fourth protocol (P4), an acupuncture needle was placed in the yin tang point. During the steps, heart rate (HR), respiratory rate (RR) and rectal temperature (RT) were measured. These evaluations were performed before treatment, fifteen minutes after drug administration, and every fifteen minutes for two hours. At the same moments, the presence or absence of decubitus, drowsiness, ptosis and other signs of tranquilization were observed. Data were statistically analyzed. In the experimental treatment (P1), one dog showed moderate tranquilization, and two dogs showed satisfactory tranquilization, without statistical difference from the group in which acepromazine was administered IM in the therapeutic dose. It can be concluded that the administration of acepromazine in subdose in the yin tang acupoint can be safely used in clinical practice, in various manipulations in which the need of tranquilization of dogs is necessary...
Se ha realizado un estudio para investigar como tranquilizar perros con acepromacina en subdosis en el punto de acupuntura yin tang, que se encuentra en el punto medio de una línea trazada entre las bordas laterales de los ojos. El estudio ha sido diseñado en cuatro protocolos utilizando ocho perros. En el primer protocolo (P1) se administró acepromacina en el punto yin tang en subdosis (0,01 mg / kg). En el segundo protocolo (P2), se administró la misma dosis usada en P1 por vía intramuscular (IM). En el tercer protocolo (P3), se administró dosis terapéutica (0,1 mg / kg) IM. En el cuarto protocolo (P4), se ha puesto una aguja de acupuntura en el punto yin tang. Durante las etapas se midieron: frecuencia cardíaca (FC), frecuencia respiratoria (FR) y la temperatura rectal (TR). Estas evaluaciones se realizaron antes del tratamiento, quince minutos después de la administración del fármaco, y a cada quince minutos durante dos horas. En los mismos momentos se ha investigado la presencia o ausencia de decúbito, somnolencia, ptosis de pálpebra y otras señales de tranquilidad. Los datos han sido analizados estadísticamente. En el tratamiento experimental (P1), dos perros mostraron tranquilidad satisfactoria y un perro moderada, lo que no fue significativamente diferente del grupo donde se administró dosis terapéutica de acepromacina por vía intramuscular. Se concluyó que la administración de acepromacina en subdosis en el punto yin tang puede ser utilizado con seguridad en la práctica clínica en las más diversas manipulaciones en las que hay la necesidad de tranquilizar perros...
Subject(s)
Animals , Dogs , Acupuncture/classification , Acupuncture/methods , Tranquilizing Agents/administration & dosage , Tranquilizing Agents/analysisABSTRACT
Seis animais foram submetidos à farmacupuntura com tiletamina e zolazepam intramuscular (Grupo I) e seis (Grupo II) receberam 10% da dose no acuponto yintang. Os do grupo GI permaneceram em decúbito lateral. Depois de 20 minutos, dois apresentaram sonolência com capacidade de locomoção durante todo período de avaliação e um permaneceu em decúbito esternal. Todos os coelhos do grupo II apresentavam aos 20 minutos em decúbito esternal. Notou-se em ambos os grupos a presença dos reflexos corneal, auricular, interdigital e palpebral. Nos animais do GI ocorreu aumento significativo dos leucócitos e nos dois grupos observou-se aumento de eritrócitos, hematócrito e plaquetas. A associação tiletamina-zolazepam, quando administrado no acupontoyintang ocasiona modificações moderadas dos parâmetros fisiológicos e alterações hematológicas, sem alterar as funções fisiológicas dos coelhos. Os fármacos injetados no acuponto permitem à contenção química dos animais durante 20 minutos.(AU)
Six rabbits were submitted to pharmacopuncture with intramuscular tiletamine (Group I) and six (Group II) received 10% of the dose in the yintang acupoint. Group I remained in lateral recumbency. After 20 minutes, two presented drowsiness with the capacity of locomotion throughout the assessment period, and one remained in sternal recumbency. All rabbits in Group II stayed 20 minutes in sternal recumbency. In both groups, the presence of corneal, ear, eyelid and interdigital reflections could be noticed. In the animals in GI, there was a significant increase in leukocytes, and both groups presented an increase in erythrocytes, hematocrit and platelet count. The tiletamine-zolazepam association, when administered in the yintang acupoint, causes moderate changes in physiological parameters and hematological changes without altering the physiological functions of rabbits. The drugs injected at the acupoint allow the chemical restraint of animals for 20 minutes.(AU)
Seis animales fueron sometidos a farmacupuntura con tiletamina y zolacepam intramuscular (Grupo I) y seis (Grupo II) recibieron 10% de la dosis en el acupunto yintang. Los del grupo GI permanecieron en decúbito lateral. Después de 20 minutos, dos presentaron somnolencia con capacidad de locomoción durante todo el período de evaluación y uno permaneció en decúbito esternal. Todos los conejos del grupo II presentaron a los 20 minutos decúbito esternal. Se observó en ambos los grupos la presencia de reflejos corneal, auricular, interdigital y de párpado. En los animales del GI ocurrió aumento significativo de leucocitos y en los dos grupos se observó aumento de eritrocitos, hematocrito y plaquetas. La asociación de tiletamina-zolacepam, cuando administrado en el acupunto yintang provoca cambios moderados de los parámetros fisiológicos y alteraciones hematológicas, sin alterar las funciones fisiológicas de los conejos. Los medicamentos inyectados en el acupunto permiten la contención química de los animales durante 20 minutos.(AU)
Subject(s)
Animals , Rabbits/growth & development , Rabbits/blood , Biochemistry/classification , Hematology/classification , Tiletamine , Zolazepam/administration & dosage , Anesthesia/veterinaryABSTRACT
Acupuncture has been widely used in alternative medicine for pain relief but may have many complications due to lack of appropriate cares. Pharmacopuncture is a sort of acupuncture that injects a herbal ingredient through a thin tube for the purpose of combining the effects of the herb and acupuncture and it has many pitfalls. The agents used in pharmacopuncture are not refined for a desired effect and not produced by sterile standard processes under strict medical surveillance. We report a case of a 44-yr-old male patient who had multiple abscesses in the psoas region with fever, right low back and hip pain that began after the pharmacopuncture treatment. This case shows that although pharmacopuncture has been practiced widely, it is important that the appropriate aseptic technique should be used to prevent severe infections and other complications.